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Test Code 5107 C-Reactive Protein, High-Sensitivity (hs-CRP), Serum

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Particle enhanced immunoturbidimetric assay

Literature References:
Package insert: Cardiac C-reactive protein CRPHS. Roche Corporation 08/2013.

Specimen Requirements

Specimen Type: Plasma
Container/Tube: Mint green top
Specimen Volume: Full tube

Day(s) Test Set Up

Monday through Friday
Turnaround Time:
STAT: not available
Routine: results available 2-4 hours of receipt

Reference Values

Values >10 mg/L are consistent with infection or inflammation. When using hs-CRP to assess cardiovascular risk, 2 measurements should be taken, 2 weeks apart (averaging results). The tertile system of relative risk is recommended. The high-risk tertile has an approximate 2-fold increase in relative risk compared with the low-risk tertile. If hs-CRP is being used to assess cardiac risk and hs-CRP is >10 mg/L, patient should be examined for sources of infection; test should be repeated after infection has resolved.

<1 mg/L (low risk)

1-3 mg/L (average risk)

>3 mg/L (high risk)

Literature Reference:

Tietz Fundamentals of Clinical Chemistry, 5th Edition, Editors: Burtis CA and Ashwood ER, Chapter 27, p. 789. W.B. Saunders Company, 2014

Test Classification and CPT Coding

86141

Additional Information

For BJH Laboratory Use Only

Alternate Tube:  

1 plain red top, full

Analyte Stability:

Store serum at 2° C to 8° C for up to 8 days. For longer storage or shipment, specimen should be frozen at -20° C.

Laboratory Processing Instructions:

Test performed in BJH Core Lab.  Processed by automated line for delivery to the Cobas 8000. Completed specimens are stored refrigerated for 5 days.

LOINC Code Information

Name LOINC Code
C reactive protein by High Sensitivity method 30522-7