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Test Code 76401436 NMDA Receptor Antibody, CSF

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Indirect Immunofluorescence (IFA)

Literature References:

Anti-Glutamate Receptor (type NMDA) IFA Test Instructions, EUROIMMUN US, Version 21/02/2011      

 

Specimen Requirements

Specimen Type: CSF

Container/Tube: See Body Fluid Collection Guidlines under Special Instructions

Specimen Volume: 1ml CSF

 

Day(s) Test Set Up

Friday

 

 

Reference Values

Negative

Interpretation:  Anti-NMDA receptor IgG antibodies are a valuable marker of autoimmune encephalopathy against the NR1 subunit of glutamate receptor (type NMDA) and also associated with tumors (mostly teratomas).  Anti-NMDA receptor autoantibodies are usually accompanied by subacute neurological symptoms and signs, and not found in healthy subjects.   

Test Classification and CPT Coding

86255

Additional Information

For BJH Laboratory Use Only

Analyte Stability

CSF -    Room Temperature- 8 hours

              Refrigerated- 48 hours

              Frozen-  1 year

Laboratory Processing Instructions         

 Test performed in BJH Immunology. Spin CSF at 3000 rpm for 10 minutes.  Remove supernatant and place in a labeled tube.  Store frozen at -70ºC.

 

Special Instructions

Body Fluid Collection Guidlines