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Test Code 9386 Thyrotropin Receptor Antibody, Serum

Additional Codes

Mayo Test ID
THYRO

Reporting Name

Thyrotropin Receptor Ab, S

Useful For

Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations:

-Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans

-Diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestation of Graves disease include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests

-Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active Graves disease

-Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of Graves disease

-Assessing the risk of Graves disease relapse after antithyroid drug treatment

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation; For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  30 days

Reference Values

≤1.75 IU/L

Day(s) and Time(s) Performed

Monday through Friday 5 a.m. - 12 a.m., Saturday 6 a.m. - 6 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THYRO Thyrotropin Receptor Ab, S 5385-0

 

Result ID Test Result Name Result LOINC Value
THYRO Thyrotropin Receptor Ab, S 5385-0

Method Name

Electrochemiluminescence Immunoassay

Forms

If not ordering electronically, complete, print, and send a General Request Form (T239) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf)

Barnes-Jewish Hospital Additional Information:
For BJH Laboratory Use Only

Laboratory Processing Instructions:

BJH Chemistry will forward to the performing laboratory. Do not reject specimen if not received on ice.