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Test Code 9559 Immunoglobulin Free Light Chains, Serum

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Profile Information:

Includes kappa free light chain (FLC), lambda FLC, and kappa/lambda FLC ratio. Tests cannot be ordered separately.

Method Name:
Immunoturbidimetric

Literature Reference:

Package insert: Freelite Human Kappa Free kit for use on Roche Cobas. Insert code: SIN055, Version: 27. The Binding Site, 01/2014. 

Specimen Requirements

Specimen Type: Serum

Container/Tube: Plain red top

Specimen Volume: Full tube

 

Day(s) Test Set Up

Monday through Friday

Cut-off time: 1000

Turnaround Time:
STAT: not available
Routine: results available by 1500 the day of testing

Reference Values

KAPPA-FREE LIGHT CHAIN

0.33-1.94 mg/dL

 

LAMBDA-FREE LIGHT CHAIN

0.57-2.63 mg/dL

 

KAPPA/LAMBDA FLC RATIO

0.26-1.65

 

Literature Reference:

Katzmann JA, Clark RJ, Abraham RS, et al. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 2002;48:1437-44.

Test Classification and CPT Coding

Test Classification:

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer’s instructions.

CPT Code:

83883 x 2

Additional Information

For BJH Laboratory Use Only
Analyte Stability:

Store specimen at 2° C to 8° C for up to 4 weeks. For prolonged storage, freeze at ≤-20° C. Repeated freeze/thaw cycles should be avoided.

Laboratory Processing Instructions:

Test performed in BJH Core lab.  Processed by automated line and aliquot stored refrigerated for batch analysis.  Completed specimens are stored refrigerated for 5 days.

Specimen Transport Temperature

Ambient

LOINC Code Information

Name LOINC Code
Kappa/Lambda Free Light Chain Ratio

40844-3