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Test Code 9567 Insulin-Like Growth Factor 1 (IGF1), Blood

Performing Laboratory

St. Louis Children's Hospital

Last Reviewed

January 2018

Interpretive

Reference Range: 

Age Males Females UOM
<4 years: 20-200 20-200 ng/mL
4-6 years: 35-225 30-250 ng/mL
7-9 years: 50-250 40-300 ng/mL
10-11 years 100-400 80-450 ng/mL
12-13 years: 100-450 100-500 ng/mL
14-15 years: 120-500 100-500 ng/mL
16-17 years: 120-500 100-450 ng/mL
18-20 years: 100-400 75-400 ng/mL
21-25 years: 100-300 75-300 ng/mL
26-30 years: 75-250 50-250 ng/mL
31-40 years: 50-225 50-225 ng/mL
>40 years: 30-200 30-200 ng/mL
       
Tanner Stage Males Females UOM
1 50-265 40-450 ng/ml
2 90-470 124-440 ng/mL
3 190-475 165-470 ng/mL
4 120-420 165-480 ng/mL
5 120-370 145-400 ng/mL

 

IGF-1 assay standardized to WHO 02/254 instituted January 2016

References:

1.Siemens Immulite IGF-1 Package Insert, Rev A. 2016
2.Bidlingmaier M, Fredrich N, Emeny RT et al. J Clin Enocrinol Metab 2014;99:1712-1721

 

Critical Values: NA
Limitations: Heterophilic antibodies in human serum can react with the immunoglobulins included in the assay components causing interference with in vitro immunoassays. Samples from patients routinely exposed to animals or animal serum products can demonstrate this type of interference potentially causing an anomalous result. For diagnostic purposes, the results obtained from this assay should always be used in combination with the clinical examination, patient medical history, and other findings.
Methodology: Enzyme-labeled chemiluminescent immunometric assay

General Information

KIDDOS order name: Insulin Like Growth Factor 1
Cerner order name: IGF1
CPT Codes: 84305
LOINC Value: In process
Synonyms: Somatomedin C; IGF1

Specimen Requirements

Specimen Type: Blood

Container/Tube

Preferred: Plain, red-top Vacutainer

Acceptable: Gold/Red SST Vacutainer

Collection Volume: 2.0 mL (minimum 0.5 mL)

Patient Preparation: None

Sample Rejection:

Specimens that are grossly hemolyzed.
Mislabeled or unlabeled specimens.

Special Instructions: None

Logistics

Test Availability: Daily
Test set-up: Tuesday and Friday
Cut-off time: 01:00 a.m.
Turnaround Time: 1-3 days
Lab Testing Section: Chemistry

Lab Dept

Core Lab

Additional Information

For SLCH Laboratory use only

 

Lab Processing instructions: Centrifuge specimen to separate. Aliquot serum into conical plastic vial and place in freezer.
Processed Volume: 0.5 mL (minimum 0.2 mL) serum
Analyte Stability:

Ambient: 24 hours
Refrigerated: 24 hours
Frozen: 12 months
 
Notes: 1. Reject due to gross hemolysis (mild okay)

Barnes-Jewish Hospital Additional Information:
For BJH Laboratory Use Only
Laboratory Processing Instructions:
BJH Chemistry will forward to the performing laboratory.