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Test Code 9619 Dihydrotestosterone, Serum

Additional Codes

Mayo Test ID
DHTS

Reporting Name

Dihydrotestosterone, S

Useful For

Monitoring patients receiving 5 alpha-reductase inhibitor therapy or chemotherapy

 

Evaluating patients with possible 5 alpha-reductase deficiency

Testing Algorithm

See Steroid Pathways in Special Instructions.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  90 days

Special Instructions

Reference Values

Males

Cord blood: ≤100 pg/mL

≤6 months: ≤1,200 pg/mL

Tanner Stages  

Mean

Age

Reference Range (pg/mL)

Stage I (>6 months and prepubertal)

7.1 years

≤50

Stage II

12.1 years

≤200

Stage III

13.6 years

80-330

Stage IV

15.1 years

220-520

Stage V

18 years

240-650

>19 years: 112-955 pg/mL

 

Females

Cord blood: ≤50 pg/mL

≤6 months: ≤1,200 pg/mL

Tanner Stages  

Mean

Age

Reference Range (pg/mL)

Stage I (>6 months and prepubertal)

7.1 years

≤50

Stage II

10.5 years

≤300

Stage III

11.6 years

≤300

Stage IV

12.3 years

≤300

Stage V

14.5 years

≤300

20-55 years: ≤300 pg/mL

>55 years: ≤128 pg/mL

 

1. Pang S, Levine LS, Chow D, et al: Dihydrotestosterone and its relationship to testosterone in infancy and childhood. J Clin Endocrinol Metab 1979;48:821-826

2. Stanczyk FZ: Diagnosis of hyperandrogenism: biochemical criteria. Best Pract Res Clin Endocrinol Metab 2006;20(2):177-191

Day(s) and Time(s) Performed

Monday, Wednesday, Thursday, Friday; 9 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80327

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DHTS Dihydrotestosterone, S 1848-1

 

Result ID Test Result Name Result LOINC Value
81479 Dihydrotestosterone, S 1848-1

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Barnes-Jewish Hospital Additional Information:
For BJH Laboratory Use Only
Laboratory Processing Instructions:

BJH Chemistry will forward to the performing laboratory. Do not reject specimen if not received on ice.