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Test Code 2250 Drug Screen, Comprehensive

Performing Laboratory

Barnes-Jewish Hospital Laboratory



Testing Algorithm:
All positive screen results except for cannabinoids and benzodiazepines will be confirmed by a second method, at an additional charge.
Qualitative analysis is performed on urine specimens only. 


Method Name:

Screening: Combination of liquid chromatography/tandem mass spectrometry (LC/MS-MS), immunoassay, gas chromatography, and colorimetry. 
Confirmation: Liquid chromatography/tandem mass spectrometry (LC/MS-MS) and gas chromatography.


Specimen Requirements


Specimen Type: Urine, random

Container/Tube: Yellow-top urine collection tube or plain red-top tube (full)

Specimen Volume: 10 mL

Collection Instructions:  No additive.

Additional Information: See Urine Collection in Special Instructions for additional information.



Day(s) Test Set Up

Monday through Sunday

Turnaround Time:
 24 hours

Reference Values

None detected

Benzodiazepines are reported as a class only.


See Drugs Detectable by Comprehensive Drug Screen under Resources section for drugs detected and their sensitivity levels.

Test Classification and CPT Coding

80307-Drug screen

80320-Volatiles (84600)

80326-Amphetamines (G0480)

80359-MDA,MDEA,MDMA (G0480)

80329-Analgesics, non-opioid (G0480)

80337-Antidepressants (G0480)

80338-Antidepressants not otherwise specified (G0480)

80339-Antiepileptics (G0480)

80346-Benzodiazepines (G0480)

80353-Cocaine (G0480)

80354-Fentanyl (G0480)

80358-Methadone (G0480)

80360-Methylphenidate (G0480)

80363-Opioids (G0480)

80367-Propoxyphene (G0480)

80370-Skeletal muscle relaxants (G0480)

80373-Tramadol (G0480)

80377- Drugs not otherwise specified (G0480)


80361-Drug confirmation- Opiates (if appropriate) (G0480)

80365-Drug confirmation- Oxycodone (if appropriate) (G0480)

80356-Drug confirmation- Heroine metabolite (if appropriate) (G0480)

80345-Drug confirmation- Barbiturates (if appropriate) (G0480)

80349-Drug confirmation- Cannabinoids (if appropriate) (G0480)



Additional Information

For BJH Laboratory Use Only

Minimum volume:  7 mL

Analyte Stability:
Specimen may be stored at ambient temperature for up to 1 week. Freeze specimen after 1 week. Repeated freeze-thaw cycles should be avoided.

Laboratory Processing Instructions:
Test performed in BJH Core Lab.  Log in and deliver immediately to the toxicology area for processing.

Specimen Transport Temperature


Special Instructions

LOINC Code Information

Test Name LOINC Code
Drugs Detected 41270-0