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Test Code 9377 Sirolimus (Rapamune), Blood

Performing Laboratory

Barnes-Jewish Hospital Laboratory


Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Specimen Requirements

Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA)-Separator gel tube is not acceptable.

Specimen Volume: Full tube


Collection Instructions: Do not centrifuge.

Day(s) Test Set Up

Monday through Sunday

Cut-off time: 2330, 0600, 0900, 1200

Turnaround Time:
STAT: not available

Routine: 3 hours after cut-off time

Reference Values

Results are reported in ng/mL.
The therapeutic range for sirolimus can vary by transplant organ type and sample timing but a trough range of 4 - 20 ng/mL is typical.

Test Classification and CPT Coding


Additional Information

For BJH Laboratory Use Only

Analyte Stability:

Specimen drawn in EDTA tube may be stored for up to 7 days at 2° C to 8° C or -20° C prior to being tested. Mix freshly collected, refrigerated, or thawed specimen thoroughly prior to use. Avoid repeated freezing and thawing. 

Laboratory Processing Instructions:

Test performed in BJH Chemistry.  Log in and place in the pending specimen refrigerator. Do not centrifuge. Do not freeze. Completed specimen is stored refrigerated for 1 week.

Specimen Transport Temperature


LOINC Code Information

Name LOINC Code
Sirolimus 29247-4