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Test Code CTX Beta-CrossLaps (Beta-CTx), Serum

Reporting Name

Beta-CrossLaps (B-CTx), S

Useful For

An aid in monitoring antiresorptive therapies (eg, bisphosphonates and hormone replacement therapy) in postmenopausal women treated for osteoporosis and individuals diagnosed with osteopenia


An adjunct in the diagnosis of medical conditions associated with increased bone turnover

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type


Specimen Required

Patient Preparation:

1. Twelve hours before this blood test, do not take multivitamins or dietary supplements containing biotin or vitamin B7 that are commonly found in hair, skin and nail supplements and multivitamins.

2. Fasting.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Draw specimen prior to 10 a.m.

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 90 days
  Refrigerated  72 hours

Reference Values


<18 years: not established

18-30 years: 120-946 pg/mL

31-50 years: 93-630 pg/mL

51-70 years: 35-836 pg/mL

>70 years: not established


<18 years: not established

Premenopausal: 25-573 pg/mL

Postmenopausal: 104-1,008 pg/mL

Day(s) and Time(s) Performed

Monday through Friday; 5 a.m.-12 a.m., Saturday; 6 a.m.-6 p.m.

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
CTX Beta-CrossLaps (B-CTx), S 41171-0


Result ID Test Result Name Result LOINC Value
CTX Beta-CrossLaps (B-CTx), S 41171-0

Method Name

Electrochemiluminescence Immunoassay