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Test Code 8028 Encainide (Enkaid ), ODE and MODE

Additional Codes

Mayo Test ID

Reporting Name

Encainide (Enkaid)

Performing Laboratory

Medtox Laboratories, Inc.

Specimen Type


Specimen Required

Submit only 1 of the following:



Draw blood in a green-top (sodium heparin) tube(s). Plasma gel tube is not acceptable. Spin down and send 1 mL of sodium heparin plasma refrigerated in a plastic vial.



Draw blood in a plain red-top tube(s). Serum gel tube is not acceptable. Spin down and send 1 mL of serum refrigerated in a plastic vial.  

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Refrigerated (preferred) 14 days
  Frozen  180 days
  Ambient  72 hours

Reference Values


Reference Range: 15 - 100 ng/mL


O-Demethylencainide (ODE):

Reference Range: 100 - 300 ng/mL


3-Methoxy-ODE (MODE):

Reference Range: 60 - 300 ng/mL


10% of patients do not form therapeutic concentrations of the active metabolites, ODE and MODE. In these patients the recommended range for the encainide concentration is 300 - 1200 ng/mL.

Day(s) and Time(s) Performed

Monday through Friday

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
FENC Encainide (Enkaid) 3589-9


Result ID Test Result Name Result LOINC Value
Z1131 Encainide 3589-9
Z1157 o-Demethylencainide (ODE) 10997-5
Z1158 3-Methoxy-ODE (MODE) 10973-6

Method Name

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Barnes-Jewish Hospital Additional Information:
For BJH Laboratory Use Only
Laboratory Processing Instructions:

BJH Chemistry will forward to the performing laboratory. Do not reject specimen if not received on ice.