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Test Code LAB141 Uric Acid, Plasma

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Enzymatic (Uricase)

Literature References:

Package insert: Uric Acid UA2. Roche Diagnostics, Form No. 03183807 190, 2015-10.

Specimen Requirements

Specimen Type: Plasma
Container/Tube: Mint-green top (lithium heparin)
Specimen Volume: Full tube

Day(s) Test Set Up

Monday through Sunday

Turnaround Time:
STAT: 1 Hour

Routine: 4 Hours

Test Classification and CPT Coding

84550

Reference Values

Males

0-12 yrs: 2.0-6.0 mg/dL

> 12 years: 3.0-8.0 mg/dL


Females

0-12 years: 2.0-6.0 mg/dL
> 12 years: 2.5-7.0 mg/dL

 

Literature Reference:

1. Rifai N, Horvath AR, Wittwer AT eds: Textbook of Clinical Chemistry and Molecular Diagnostics 6 th ed: Chapter 32, p. 479, Elsevier, St. Louis, MO 2018.

2. Lim EM, Bennett P, Beilby J:  Sample Preparation in Patients Receiving Uric Acid Oxidase (Rasburicase) Therapy.  Clinical Chemistry 2003: 49:1417.

3. Town M-H, et al: J Clin Chem Biochem 1985; 23:591.

Specimen Transport Temperature

Ambient

Additional Information

For BJH Laboratory Use Only

Alternate Tube(s):

1 plain, red-top tube

1 plain, red/grey top tube

1 dark green-top (lithium heparin) tube

 

Laboratory Processing Instructions:

Test performed in BJH Core Lab.  Processed by automated line for delivery to the Cobas 8000. Completed specimens are stored refrigerated for 5 days. 

Test performed in South County Siteman and Ambulatory Cancer Building Lab.  Centrifuge sample and deliver to the Cobas.  Completed specimens are stored refrigerated for 5 days. 

For patients receiving Rasburicase:

Collection Container: Pre-chilled mint green

Collection Instructions: Elitek (Rasburicase) causes enzymatic degradation of uric acid in blood samples at room temperature, resulting in spuriously low uric acid levels. Blood should be collected in a pre-chilled tube, immediately immersed in ice water, and sent immediately to the Core Lab. Samples must be assayed within 4 hours of collection. Results < 0.5 will be commented using the comment template: RASB; "Results may be falsely decreased due to Elitek (Rasburicase)".

 

Special Instructions

See Analyte Stability Chart under General Information for a complete list.

LOINC Code Information

Name LOINC Code
Urate 3084-1