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HelpTest Code LAB468 Diazepam and Metabolites, Serum
Additional Codes
| Mayo Test ID |
|---|
| DIA |
Test Down Notes
This test is temporarily unavailable. As an alternate, order ZW86(1501SP). For additional details, see test update here.
Reporting Name
Diazepam and metabolites, SUseful For
Assessing compliance
Monitoring for appropriate therapeutic level
Assessing diazepam toxicity
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reference Values
Therapeutic concentrations
Diazepam: Not established
Diazepam and Nordiazepam: 100-2,500 ng/mL
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Diazepam: 10 ng/mL
Nordiazepam: 10 ng/mL
Oxazepam: 10 ng/mL
Temazepam: 10 ng/mL
Day(s) Performed
Wednesday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DIA | Diazepam and metabolites, S | 49044-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8629 | Diazepam | 3548-5 |
| 2475 | Nordiazepam | 3537-8 |
| 2459 | Diazepam and Nordiazepam | 16757-7 |
| 622868 | Oxazepam | 3886-9 |
| 622869 | Temazepam | 10343-2 |
Report Available
3 to 7 daysMethod Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
For BJH Laboratory Use Only
Alternate Tube:
1 dark green-top (lithium heparin) tube
1 pink-top (EDTA) tube
Separator gel tube is not acceptable.
Laboratory Processing Instructions:
BJH Chemistry will forward to the performing laboratory. Do not reject specimen if not received on ice.