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Test Code LAB5758 Smooth Muscle Antibodies, Serum

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Indirect Immunofluorescence

Testing Algorithm:

If smooth muscle antibody is positive, smooth muscle antibody titer will be performed, at an additional charge.

Literature References:

Package insert Nova Lite ANA Plus mouse kidney and stomach July 2018.

Specimen Requirements

Specimen Type: Serum

Container/Type: Plain red top

Specimen Volume: Full tube

 

Day(s) Test Set Up

Monday, Wednesday, Friday

Cut-off time: 0800

Turnaround Time:
STAT: not available
Routine: results available the day of testing

Test Classification and CPT Coding

86015-Smooth Muscle Ab
86015-Smooth Muscle Ab titer (if appropriate)

Reference Values

Smooth Muscle Antibodies

Interpretation

≤ 1:20

Negative

> 1:20

May be present in acute viral hepatitis, lupoid hepatitis, infectious mononucleosis, and malignancy.

> 1:80

Highly suggestive of chronic active hepatitis.

 

Literature References:

1. Alvarez F, Berg P, Bianchi F, Bianchi L, Burroughs AK, Cancado EL, et al. International autoimmune hepatitis group report: a review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-38.

2. Czaja AJ, Norman GL. Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota and INOVA Diagnostics, San Diego, California. Autoantibodies in the diagnosis and management of liver disease. J Clin Gastroenterol 2003;37:315-29.

Specimen Transport Temperature

Ambient

Additional Information

For BJH Laboratory Use Only

Alternate Tube:

SST Red top

Gold Top (serum SST)

Laboratory Processing Instructions:

Test performed in BJH Core Lab. Processed by automated line and aliquot stored frozen for batch analysis. Completed specimens are stored refrigerated for 5 days.

Note: #5027 Mitochondrial Antibodies, Serum is performed on the same slide. If positive, results will be reported at no charge. Titer will not be performed.

LOINC Code Information

Name LOINC Code
Smooth Muscle Antibodies, Serum 26971-2