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Test Code LAB714 Ethylene Glycol, Serum

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Enzymatic, glycerol dehydrogenase

 

Literature Reference:

Package insert: Ethylene Glycol, Catachem., Oxford, Connecticut, 09/2021.

Specimen Requirements

Specimen Type: Serum

Container/Tube: Plain red top-Separator gel tube is not acceptable.

Specimen Volume: Full tube

 

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT:  1 hour after receipt in laboratory.

Routine: 2-4 hours after receipt in laboratory.

GC confirmation performed on initial results ≥ 10 mg/dL.  Confirmation reported within 24 hours.

 

Test Classification and CPT Coding

82693-Ethylene Glycol

 

Reference Values

Normal:  < 10 mg/dL (None Detected)
Critical result (automatic call-back): any detectable amount (level of detection is ≥ 10 mg/dL).

 

Any first-time critical value ≥ 10 mg/dL will be confirmed with gas chromatography (GC) to confirm the results. Subsequent critical results obtained on the same patient within 96 hours of the first confirmed critical do not require GC confirmation.

 

NOTE:  Propylene Glycol interferes with this assay.  Specimens containing propylene glycol should not be monitored using this assay.  

 

Interpretative Data:

This test was developed using an analyte specific reagent and its performance characteristics were determined by the Barnes-Jewish Hospital Laboratory.  The lab is regulated under CLIA as qualified to perform high-complexity testing.  This test has not been cleared or approved by the U.S. Food and Drug Administration.  This test is intended for clinical purposes.  Current interpretive data was last revised on 10/24/2022.

 

Literature References:

1. Baselt RC, Cravey RH, eds. Ethylene glycol. In: Disposition of toxic drugs and chemicals in man. Chicago: Year Book Medical Publishers, 1898:337-41.

2. Turk J, Morrell L, Avioli L. Arch Int Med 1986;146:1601-3.

3. Ellenhorn MJ, Barceloux DG, eds. Ethylene glycol. In: Medical toxicology: the diagnosis and treatment of human poisoning. New York: Elsevie, 1988:805-9.

 

Specimen Transport Temperature

Ambient < 2 days

Additional Information

For BJH Laboratory Use Only
Alternate Tube:

None


Analyte Stability:

  • Specimens must be processed within 2 days.
  • Processed sample stability:
    • Ambient - 2 days
    • Refrigerated (2 - 8°C) - 5 days
    • Frozen (≤ -20°C) - 1 month
  • See Analyte Stability Chart under General Information for a complete list.

Repeated freeze-thaw cycles should be avoided.

 

Laboratory Processing Instructions:

Test performed in the BJH Core Lab. Samples will be delivered immediately to the cobas 8000.    

LOINC Code Information

Name LOINC Code
Ethylene Glycol, serum 5646-5
Ethylene Glycol Confirmation 23713-1