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HelpTest Code LAB7780 Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum
Useful For
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
Diagnosis of autoimmune AQP4 channelopathy
Diagnosis of neuromyelitis optica (NMO)
Distinguishing NMOSD from multiple sclerosis early in the course of disease
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NMOTS | NMO/AQP4 FACS Titer, S | No | No |
Testing Algorithm
When the results of this assay require further evaluation, NMOTS / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Titer Assay, Serum will be performed at an additional charge.
Method Name
Flow Cytometry
Reporting Name
NMO/AQP4 FACS, SSpecimen Type
SerumOrdering Guidance
Specimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reference Values
Negative
Day(s) Performed
Monday, Tuesday, Thursday
Report Available
5 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86053
86053-titer (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NMOFS | NMO/AQP4 FACS, S | 43638-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 38324 | NMO/AQP4 FACS, S | 43638-6 |
Forms
If not ordering electronically, complete, print, and send Neurology Specialty Testing Client Test Request (T732) with the specimen.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Call Laboratory Medicine resident at digital pager 314-747-1320 for approval before drawing the specimen.