Sign in →

Test Code LAB818 Creatinine Clearance, Plasma and 24-Hour Urine

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Enzymatic (Creatininase)
Includes #LAB66 Creatinine, Plasma; #LAB712 Creatinine, 24 Hour, Urine; and calculation of creatinine clearance.

Literature Reference:

Package insert: Creatinine CREP2 reagent. Roche Corporation, 02/2019.

Specimen Requirements

Plasma and urine are required.

 

Specimen Type: Plasma

Container/Tube: Mint-green top (lithium heparin)

Specimen Volume: Full tube

Collection Instructions: Plasma should be drawn midway into urine collection period. However, morning blood draw is acceptable.

 

Specimen Type: Urine, 24 hour

Container/Tube: Plain, brown urine container

Specimen Volume: Entire collection

Collection Instructions: No additive. Refrigerate specimen during collection.

Additional Information:

1. Starting and ending times of collection are required.
2. See Urine Collection information under General Information.
3. Specimen collected in a container with either 6N HCl or Boric Acid is acceptable. 

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT: Not available
Routine: 2 to 4 hours after receipt in laboratory

Test Classification and CPT Coding

82575-Creatinine clearance

Reference Values

CREATININE CLEARANCE
60 - 130 mL/minute
See individual test listings for other reference intervals.

Literature Reference:

1. Rifai N, Horvath AR, Wittwer AT eds: Textbook of Clinical Chemistry and Molecular Diagnostics 6th ed: Chapter 5, p. 1256, Elsevier, St. Louis, MO 2018.  

2. Sanger AK, Lockwood C, Snozek CL, Karon BS, Scott MG, Jaffe A. Catecholamine Interference in Enzymatic Creatinine Assays.  Clin Chem 2009; 55:1732.

Specimen Transport Temperature

Ambient

Additional Information

For BJH Laboratory Use Only
Alternate Tube:

Creatinine, plasma

1 dark green-top (lithium heparin) tube
1 red-top tube

Urine

Specimen collected in a container with either 6N HCl or Boric Acid is acceptable.
Analyte Stability:

Urine specimen must be kept refrigerated during the collection and before delivery to limit bacterial growth.

Laboratory Processing Instructions:

Test performed in BJH Core Lab.

Plasma: Processed by automated line for delivery to the Cobas 8000. Completed specimens are stored refrigerated for 5 days. 


Urine:  Mix urine well. Record volume, period, and pH on request form. Using 13x100 test tubes, prepare a 7-mL aliquot and deliver to the automated line for centrifugation and delivery to Cobas 8000 for analysis. Completed specimen is stored refrigerated for 5 days.

Special Instructions

See Urine Collection information under General Information.

See Analyte Stability Chart under General Information for a complete list.

LOINC Code Information

Name LOINC Code
Creatinine, plasma 2160-0
Creatinine renal clearance in 24 hour urine 2164-2
Collection duration 13362-9
Volume of urine 19153-6