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Test Code 8141 ChromoSeq - Heme Genetic Profiling (WGS) with Interpretation

Test Details

ChromoSeq™ is a whole genome sequencing (WGS) assay intended for the comprehensive clinical genomic evaluation of known or suspected hematologic neoplasms including AML and MDS

 

ChromoSeq™ is capable of unbiased detection of chromosomal translocations, copy number alterations, single nucleotide variants, and insertions/deletions from DNA. The assay can also provide data in the setting of failed or incomplete cytogenetics.

 

ChromoSeq_requisition

 

Note: ChromoSeq™ testing will be resulted with a professional interpretation. If providers wish to opt out of the interpretation, please notate that in the “comments” section of the order.

 

For additional questions regarding testing, pre-autorization, or results, contact the Clinical Support Office at cso@path.wustl.edu or 314-747-1100.

 

 

 

Relevant Conditions

  • Acute Myeloid Leukemia (AML)
  • Myelodysplastic Syndrome (MDS)

Methodology

Whole Genome Sequencing

Testing Frequency and Turnaround Time

Testing batched in a bi-weekly set-up; results available within approximately 21 business days.

Specimen Requirements

Specimen Type: Bone Marrow Aspirate or Peripheral Blood collected within 14 days

Container: K2EDTA vacutainer

Specimen Volume: minimum 0.5 mL, preferred 1.0 mL

Additional Information: Ship at room temperature within 72 hours of collection.

 

Unacceptable specimen conditions include fresh or FFPE tissue, incorrect specimen container, or unlabeled specimen.

CPT Code

81479