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Test Code LAB150 C-Reactive Protein, High-Sensitivity (hs-CRP) Cardiac Risk

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Particle enhanced immunoturbidimetric assay

Literature References:
Package insert: Cardiac C-reactive protein CRPHS. Roche Corporation 02/2022.

Specimen Requirements

Specimen Type: Plasma
Container/Tube: Mint green top
Specimen Volume: Full tube

Day(s) Test Set Up

Monday through Friday
Turnaround Time:
STAT: not available
Routine: results available 2-4 hours of receipt

Test Classification and CPT Coding

86141

Reference Values

Adult Only 

Interpretive data: Values greater than or equal to 10mg/L are consistent with infection or inflammation. Individuals with evidence of active infection, systemic inflammatory processes, or trauma should not be tested until these conditions have abated when using hsCRP to assess cardiovascular risk. Two measurements should be taken two weeks apart (averaging results). The CDC/AHA recommended the following hsCRP cut off points (tertiles) for CVD assessment.

Low risk <1.0 mg/L 

Average risk 1.0-3.0 mg/L

High risk >3.0 mg/L

Literature References:
Package insert: Cardiac C-reactive protein CRPHS. Roche Corporation 02/2022.

Additional Information

For BJH Laboratory Use Only

Alternate Tube:  

1 plain red top, full

Analyte Stability:

See analyte stability chart.

Laboratory Processing Instructions:

Test performed in BJH Core Lab.  Processed by automated line for delivery to the Cobas 8000. Completed specimens are stored refrigerated for 5 days.

LOINC Code Information

Name LOINC Code
C reactive protein by High Sensitivity method 30522-7