Test Code LAB489 Protein C Activity, Plasma
Performing Laboratory
Barnes-Jewish Hospital Laboratory
Methodology
Chromogenic
Literature References:
HemosIL Protein C (pn20300500) package insert issued 01/2007, Instrumentation Laboratory.
Specimen Requirements
Specimen Type: Blood
Container/Tube: Light-blue top (citrate)
Specimen Volume: Full tube
Specimen Minimum Volume: 1 Full tube
Collection Instructions:
- Draw a discard blue top tube prior to drawing a light-blue top (citrated) tube if using a Winged Infusion Set. Discard tube should be under filled and discarded.
- Clotted blood or an insufficient specimen is not acceptable.
- Avoid phlebotomy techniques which cause hemolysis and heparin contamination.
- Follow nursing policy on volume of blood to discard prior to collecting blood from indwelling heparinized catheters.
Analyte Stability:
4 hours at 18° C to 24° C.
Platelet-free plasma can be frozen at -20 for transport on dry ice up to 72 hours
or stored 6 months at -70° C.
Additional Information: If the patient is a hospital patient and the hematocrit is >55%, call Barnes-Jewish Hematology Laboratory at 314-362-5203 for instructions.
Day(s) Test Set Up
Monday, Wednesday, and Friday
Cut-off time: 0700
Turnaround Time:
STAT: not available
Routine: results available the day of testing
Test Classification and CPT Coding
85303
Reference Values
60%-150%
Numerous drugs and clinical conditions affect the plasma concentration of the protein.
Literature References:
1. Griffin JH, Evatt B, Zimmerman TS, et al. Deficiency of protein C in congenital thrombotic disease. J Clin Invest 1981;68:1370-3.
2. Comp PC, Nixon RR, Esmon CT. Determination of functional levels of protein C, an antithrombotic protein, using thrombin-thrombomodulin complex. Blood 1984;63:15-21.
Specimen Transport Temperature
Ambient Yes/Refrigerate NO/Frozen Yes
Additional Information
For BJH Laboratory Use Only
Analyte Stability:
4 hours at 18o C to 24o C.
Platelet-free plasma can be frozen at -20 for transport on dry ice up to 72 hours
or stored 6 months at -70° C.
Laboratory Processing Instructions:
Test performed in BJH Core Lab.
LOINC Code Information
Name | LOINC Code |
Protein C Activity, Plasma | 6006-1 |