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Test Code LAB494 Rapid Plasma Reagin (RPR) Qualitative, Serum

Infectious

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Particle Agglutination

Testing Algorithm:

If RPR is reactive, then RPR quantitative and treponemal antibody confirmation may be performed, at an additional charge.

Literature Reference:

1. Larsen SA, Hunter EF, Kraus SJ, eds. A manual of tests for syphilis. Washington, D.C.: American Public Health Association, 1990.

2. BD Macro-Vue RPR Card Test Instructions for Use. Becton Dickinson and Company. May 2021.

3. Tesfazghi MT, Anderson NW, Gronowski AM, Yarbrough ML. 2019. Clinical performance of the BioPlex 2200 Syphilis Total & RPR assay at a tertiary medical center with a high rate of syphilis. J Clin Microbiol 57:e01487-18.

Specimen Requirements

Specimen Type: Serum
Container/Tube: Plain red top, Red/grey or Gold
Specimen Volume: Full tube

Specimen Minimum Volume: 1 mL

Day(s) Test Set Up

Monday through Sunday

Turnaround Time:
STAT: 2 hours after receipt in laboratory
Routine: results available the day of testing

Test Classification and CPT Coding

86592 RPR Qualitative

86593 RPR Quantitative ( if appropriate)

86780 Treponemal Antibody ( if appropriate)


 

Reference Values

Reference: Nonreactive

Reported as Nonreactive, Reactive

 

.

Specimen Transport Temperature

Ambient

Additional Information

Prozone Request: Providers or LMR, please call Customer Service at 314-362-1470 to request Prozone testing.

For BJH Laboratory Use Only

Additional specimen type: EDTA (pink or purple).  If testing being added to CBC specimen, ensure specimen is spun before testing.

Specimen Volume, Minimum: Full tube, 1mL minimum

Prozone: Customer service will call and speak to set-up tech with accession number for Prozone testing. Set-up tech will follow SOP related to Prozone requests.

Analyte Stability:

Serum: 2° C to 8° C for <5 days or -20° C for 6 months (serum removed from RBCs).

Plasma: 2° C to 8° C for 24 hours

 

LOINC Code Information

Name LOINC Code  
Rapid Plasma Reagin(RPR) 22461-8  
Rapid Plasma Reagin (RPR) titer 11084-1