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Test Code LAB4958 Pain Management Profile 

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Methodology

Profile Information: This order includes a Drug Screen with Confirmation and a Targeted Opioid Panel performed by LC-MS/MS. 

Amphetamines (AMP/METH) Methadone
Barbiturates Opiates
Benzodiazepines Screen Oxycodone
Cannabinoids Screen Phencyclidine
Cocaine Metabolite Buprenorphine
Oxymorphone  O-desmethyltramadol
Norbuprenorphine Tramadol
Methadone Metabolite(EDDP) 6 Acetyl-Morphine
Tapentadol Hydrocodone
Hydromorphone Codeine
Morphine Naloxone
Fentanyl 7OH-Mitragynine

 

Method Name:

Screen: Kinetic interaction of microparticles in solution (KIMS)

Targeted Opioid Panel: Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Confirmation: LC-MS/MS

 

Testing Algorithm:

Results below cutoff are reported as Not Detected.

Results above cutoff are reported as Screen Positive, presumptive.

For drug cutoff information refer to the individual drug analyte.

All positive drug screens by immunoassay, except for cannabinoids and barbiturates will be automatically confirmed by LC-MS/MS, at an additional charge.

 

Literature Reference:

See individual test listings.

Specimen Requirements

Specimen Type: Urine, random

Container/Tube: Yellow-top urine collection tube or plain red-top tube (full)

Specimen Volume: 10 mL

Collection Instructions: No additive.

 

Additional Information: 

The targeted opioid panel detects both free and conjugated drug metabolites and is performed by liquid chromatography tandem mass spectrometry.  7OH-Mitragynine includes detection of both 7OH-mitragynine and mitragynine, also known as kratom.

 

Questions concerning interpretation should be directed to the laboratory.  The results of this test are intended for clinical use.  This test was developed and its performance characteristics determined by Barnes Jewish Hospital Clinical Laboratory.  It has not been cleared or approved by the U.S. Food and Drug Administration.

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT: Drug Screen results available 1 hour after receipt in laboratory. Targeted Opioid Screen and Confirmation of Detected results within 24 hours. 
Routine: Drug Screen results available 3 hours after receipt in laboratory. Targeted Opioid Screen and Confirmation of Detected results within 24 hours. 

Test Classification and CPT Coding

80307-Drug screen

80364-Targeted Opioid Screen

80324-Drug confirmation- Amphetamines (if appropriate) (G0480)

80359-Drug confirmation- MDA,MDEA,MDMA (if appropriate) (G0480)

80356-Drug confirmation- Heroine metabolite (if appropriate) (G0480)

80353-Drug confirmation- Cocaine (if appropriate) (G0480)

83992-Drug confirmation- Phencyclidine (if appropriate) 

80354-Drug confirmation- Fentanyl (if appropriate) (G0480) 

Reference Values

None detected

Cannabinoids are reported as Screen Positive, presumptive or Not Detected.  Barbiturates are reported as Screen Positive, presumptive or Not Detected; confirmation is performed by Mayo Medical Laboratories only upon request, at an additional charge.   

Specimen Transport Temperature

Ambient

Additional Information

For BJH Laboratory Use Only
Sample Stability:

  • Ambient - 2 days
  • Refrigerated (2-8°C) - 7 days
  • Freeze specimen for longer storage 

 

Laboratory Processing Instructions:

Test performed in BJH Core Lab.  Processed by automated line for delivery to the Cobas 8000 and the Waters LC-MS/MS for confirmation. Completed confirmations are stored frozen for 30 days. 

Special Instructions

LOINC Code Information

Name LOINC Code
Amphetamine/Methamphetamine 43983-6
Barbiturates 70155-7
Benzodiazepines Screen 14316-4
Cannabinoids Screen 70145-8
Cocaine Metabolite 43984-4
Methadone 70149-0
Opiates 70151-6
Oxycodone 19642-8
Phencyclidine 14310-7
Fentanyl 59673-4