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HelpTest Code LAB526 Insulin-Like Growth Factor 1 (IGF1), Blood
Performing Laboratory
St. Louis Children's Hospital
Last Reviewed
November 2024
Specimen Requirements
Specimen Type: Blood
Container/Tube
Preferred: Mint green-top (lithium heparin) Vacutainer®.
Acceptable: Gold/Red SST Vacutainer® or Plain, red-top Vacutainer®.
Collection Volume: 2.0 mL (minimum 0.6 mL)
Patient Preparation: Sample should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours following the last biotin administration.
Sample Rejection:
Specimens that are grossly hemolyzed.
Mislabeled or unlabeled specimens.
Special Instructions: None
Specimen Tube: Light green-top (Lithium Heparin) is preferred tube type
Interpretive
Reference Range:
|
Age: years |
Male |
Female |
|
<2 |
10-200 |
10-200 |
|
2-3 |
10-250 |
10-250 |
|
3-4 |
20-250 |
20-250 |
|
4-5 |
30-250 |
30-250 |
|
5-6 |
40-250 |
40-250 |
|
6-7 |
50-275 |
45-250 |
|
7-8 |
50-300 |
45-300 |
|
8-9 |
60-350 |
50-350 |
|
9-10 |
70-400 |
60-400 |
|
10-11 |
70-450 |
70-500 |
|
11-12 |
80-500 |
90-600 |
|
12-13 |
85-550 |
100-650 |
|
13-14 |
90-600 |
110-700 |
|
14-15 |
95-620 |
115-750 |
|
15-16 |
100-650 |
120-700 |
|
16-17 |
100-650 |
120-600 |
|
17-18 |
100-600 |
120-500 |
|
18-20 |
90-500 |
100-400 |
|
20-22 |
80-400 |
80-350 |
|
23-25 |
65-350 |
70-320 |
|
26-30 |
60-330 |
65-300 |
|
31-35 |
55-300 |
60-280 |
|
36-40 |
50-300 |
55-250 |
|
41-45 |
45-275 |
50-250 |
|
46-50 |
40-250 |
45-230 |
|
51-55 |
35-250 |
40-210 |
|
56-60 |
35-230 |
35-200 |
|
≥61 |
30-200 |
30-200 |
|
|
|
|
|
Tanner Stage |
|
|
|
I |
80-250 |
80-320 |
|
II |
100-450 |
120-450 |
|
III |
250-500 |
250-550 |
|
IV |
225-600 |
225-600 |
|
V |
225-500 |
180-500 |
|
|
|
|
|
Assay calibrated to WHO 02/254 and instituted at SLCH 5/2018. Current interpretive criteria established 5-10-2018. References: |
||
|
1. Elecsys IGF-1 Package Insert 2017-10, V 1.0 |
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|
2. Mayo Medical Laboratories IGFMS entry (https://www.mayomedicallaboratories.com/test-catalog/Overview/62750) accessed 5-9-2018. |
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|
3. Bidlingmaier M, Fredrich N Emen RT et al. J Clin Endocrinol Metab 2014;99:1712-1721 |
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Critical Values: None established
Limitations: Sample should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours following the last biotin administration.
Methodology: Sandwich principle
General Information
EPIC order name: Insulin Like Growth Factor (EPIC Test#LAB526)
Cerner order name: IGF1
CPT Codes: 84305
LOINC Value: In process
Synonyms: Somatomedin C; IGF1
Logistics
Test Availability: Daily
Test set-up: Monday-Sunday
Cut-off time: None; performed as received.
Turnaround Time: Same day, results available 2 hours from receipt in lab
Lab Testing Section: Chemistry
Lab Dept
Core Lab
Additional Information
For SLCH Laboratory use only
Lab Processing instructions: Centrifuge specimen to separate. If specimen is collected in plain, red-top tube aliquot sample into a conical tube for testing (labeling aliquot tube as 'serum').
Processed Volume: 0.5 mL (minimum 0.3 mL) serum
Analyte Stability:
Ambient - unprocessed: 8 hours
PROCESSED
Ambient: 24 hours
Refrigerated: 48 hours
Frozen: 28 days
Notes: Will also accept Lavender-top (EDTA) plasma; making sure aliquot is labeled as "EDTA plasma"
For BJH Laboratory Use Only
Specimen Tube: Light green-top (Lithium Heparin) is preferred tube type
Laboratory Processing Instructions:BJH Core Laboratory will forward to the performing laboratory.