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HelpTest Code LAB863 Epstein-Barr Viral Antibody Panel, Serum
Infectious
Performing Laboratory
Barnes-Jewish Hospital Lab
Methodology
Multiplex Flourescent Immunoassay
Testing for Epstein-Barr Viral Capsid IgG, Epstein-Barr Viral Capsid IgM and Epstein-Barr Nuclear Antigen IgG
Literature Reference:
1. EBV IgG package insert. Bio-Rad Laboratories, Inc. 2/2025
2. EBV IgM package insert. Bio-Rad Laboratories, Inc. 9/2025
3. Stevens CD.Clinical immunology and serology:a laboratory perspective.2nd ed. Davis, 2003:330-2
4. Henry JB. Clinical diagnosis and management by laboratory methods, 20th ed. Saunders, 2001:593-5, 56-7
5. Straus SE, Cohen JI, Tosato G, Meier J. Epstein-Barr virus infections: biology, pathogenesis and management (NIH Conference), Ann Intern Med 1993; 118:45-58
Specimen Requirements
Specimen Type: Serum only
Container/Tube: Plain red top, Red/grey SST or Gold SST
Specimen Volume: Full tube, minimum 1mL of serum
Day(s) Test Set Up
Monday - Sunday 0700 - 1300
Turnaround Time:
STAT: not available
Routine: result available to day of testing
Test Classification and CPT Coding
86665 Epstein-Barr virus, viral capsid IgG
86665 Epstein-Barr virus, viral capsid IgM
86664 Epstein-Barr virus, nuclear antigen IgG
Reference Values
EBV IgG - Negative
EBV IgM - Negative
EBV NA - Negative
Interpretive Data
EBV IgG
|
Results |
Interpretation |
|
Negative |
No Interpretation |
|
Equivocal |
Presence of antibodies cannot be determined. Recommend follow up testing in 10-14 days if clinically indicated. |
|
Positive |
No Interpretation |
EBV IgM
|
Negative |
No Interpretation |
|
Equivocal |
Presence of antibodies cannot be determined. Recommend follow up testing in 10-14 days if clinically indicated. |
|
Positive |
No Interpretation |
EBV NA
|
Negative |
No Interpretation |
|
Equivocal |
Presence of antibodies cannot be determined. Recommend follow up testing in 10-14 days if clinically indicated. |
|
Positive |
No Interpretation |
EBV PANEL Interpretation Algorithm
|
EBV VCA IgM |
EBV VCA IgG |
EBV NA |
Interpretation |
Report comment |
|
Neg |
Neg |
Neg |
Negative |
No antibody detected. |
|
Pos |
Neg |
Neg |
Current Infection |
Suggestive of current infection. |
|
Pos |
Pos |
Neg |
Current Infection |
Suggestive of current infection. |
|
Neg |
Pos |
Neg |
Recent Infection |
Results indicate infection with EBV, but the time since primary infection cannot be determined due to the absence of both VCA IgM and EBNA IgG. Suggest repeat testing in 2-3 weeks if clinically indicated. |
|
Pos |
Pos |
Pos |
Recent Infection |
Suggestive of a recent infection. |
|
Neg |
Pos |
Pos |
Past Infection |
Suggestive of a past infection. |
|
All other result combinations including Equivocal. |
No definitive interpretation |
This specimen exhibits an unusual antibody profile. |
||
Specimen Transport Temperature
Ambient
Additional Information
Specimen Stability:
Analyte Stability: Avoid hemolysis. Refer to analyte stability chart.
Laboratory Processing Instructions: Test performed in the Core Lab. Processed by automated line for delivery to OBS3 with a minimum of 1mL of plasma/serum. Completed specimens are stored refrigerated for 7 days.
LOINC Code Information
|
Epstein Barr Virus, VCA IgG |
5157-3 |
|
Epstein Barr Virus, VCA IgM |
5159-9 |
|
Epstein Barr Virus, NA IgG |
30083-0 |